Anyone who has ever attempted to crystallise a protein or other biological macromolecule has encountered at least one. if not all of the following scenarios: No crystals at all. tiny low quality crystals; phase separation; amorphous precipitate and the most frustrating; large. beautiful crystals that do not diffract at all. https://www.lightemupsequences.com/quick-find-Our-Seasons-The-World-in-Winter-Spring-Summer-and-Autumn-best-save/