You will find there's launch of norepinephrine from your descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to lessen afferent pain transmission and develop analgesia. For that reason, medicines like clonidine that goal alpha-two receptors can influence the transmission of pain. Jun 10, 2024 https://spiroj638ndt4.bloggip.com/profile