Pentobarbital will decrease the level or effect of roflumilast ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not recommended; strong cytochrome P450 enzyme inducers decrease systemic exposure to roflumilast knipa may reduce the therapeutic effectiveness pentobarbital decreases levels of panobinostat ort affecting hepatic/intestinal enzyme... https://beckettsurnm.dm-blog.com/30255384/vad-är-natriumpentobarbital-en-översikt