-dihydroxyphenyl rings of procyanidin C1 ended up present in the framework mimicking K2E2·Pi condition. This interaction triggers the ion pathway (which happens to be fashioned by residues which include among the interacting arginines, R979) to become inaccessible in the extracellular side76. This binding mode might Hence sterically impede ion exchange. https://paxtontafkn.widblog.com/84564515/the-smart-trick-of-il-4-protein-that-nobody-is-discussing