Olanzapine/samidorphan will reduce the level or influence of hydromorphone by pharmacodynamic antagonism. Contraindicated. Samidorphan elicits opioid antagonistic results and will increase danger of precipitating acute opioid withdrawal in individuals depending on opioids. Opioid Analgesic REMS: Making sure that the advantages of opioid analgesics outweigh the challenges of habit, abu... https://sparkyq318lzk2.blue-blogs.com/profile