Jamieson described the development of MF from the context with the JAK/STAT network. “This pathway is upregulated in virtually all sufferers with these myeloproliferative neoplasms. In some, It is according to a mutation in JAK2 that forestalls the gene from staying turned off; in Other folks, a mutation in CALR https://titusdilux.blogoscience.com/32100030/detailed-notes-on-navitoclax